Lysimachia christinae.  Jīn qiān căo, Kuo lu huang   Lysimachia    Family: Primulaceae     
Jin qian cao generally refers to Lysimachia christinae in the Pharmacopoeia of the People's Republic of China, but in the West- Desmodium styracifolium may be more commonly encountered.[3] Similar to Glechoma hederacea
PART USED: Dry whole plant- harvested inSummer or Autumn.
   FLAVOR: Bland. Bitter and sour CHANNELS: Bladder, Gall bladder, Kidney, Liver
FUNCTIONS
GROUP: Diuretic- very important herb for treating stones in both the urinary and biliary tracts.
1. Promotes urination,[1,4]remove stones.[4]
2. Detoxifies and reduces swelling and inflammation.[1,4]
3. Clear Heat, benefit Gall bladder.[4] Remove Gall bladder stones.[4]
INDICATIONS
1. Unblocks dysuria and expels stones of the urinary tract.[1,4]
2. Jaundice, red swollen eyes due to Damp Heat.[4] Gall bladder stones.[1,4]
3. Pus forming inflammations, burn injuries, abscesses, poisonous snake bites.[1,4]
4. Mushroom poisoning, drug poisoning.[1]
CONTRAINDICATIONS: When a large dosage of this herb is taken long-term, patients can develop dizziness and/or palpitations. This is attributed to depletion of potassium from the body oweing to the herbs diuretic effect.[4]
PATENT COMBINATIONS
COMBINATIONS
PREPARATIONS: 15-60 g.[2,4] Often used alone or as an infusion for stones.[4]


HABITAT: Grows in grassy thickets along roadsides.
DESCRIPTION: Perennial herb. The whole plant sparsely pubescent. Stems; soft and weak, prostrate. Leaves, calyx and corolla covered by black dots and stripes. Leaves opposite, ovate or cordate, apexes obtuse, bases rounded or cordate, margins intact. Length of petiole and leaves approximately the same. Flowers; in summer, single axillary yellow flowers. Capsule; globular.
References
Inner Path can not take any responsibility for any adverse effects from the use of plants. Always seek advice from a professional before using a plant medicinally.

Constituents

References

Evaluation of the antioxidant and endothelial protective effects of Lysimachia christinae Hance (Jin Qian Cao) extract fractions.

Wu NH, Ke ZQ, Wu S, Yang XS, Chen QJ, Huang ST, Liu C.
Abstract
BACKGROUND:
Lysimachia christinae Hance is a traditional Chinese medicine with diuretic, detumescent, and detoxifying effects. Our aimed to optimize the extraction protocol to maximize the yield of flavonoids from Lysimachia christinae Hance, and evaluate the pharmacological activities of four fractions, namely, petroleum ether (PE), ethyl acetate (EA), n-butanol (NB), and aqueous (AQ) fractions, of the ethanolic extract of Lysimachia christinae Hance.
METHODS:
The flavonoid monomers in the crude extract were characterized via high performance liquid chromatography (HPLC), were used as markers for extract quality control and standardization. The total flavonoid, total phenolic, and total polysaccharide contents of each fraction were determined by spectrophotometry. Further, the in vitro free radical (diphenylpicrylhydrazyl, 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid), superoxide, and hydroxyl radicals) scavenging activities, and antioxidant capacity in endothelial cells were evaluated for each fraction.
RESULTS:
After optimizing the extraction protocol to maximize the total flavonoid yield from L. christinae Hance, the NB fractions had the highest total flavonoid (39.4  ± 4.55 mg RE/g), total phenolic (41.1 ± 3.07 mg GAE/g) and total polysaccharide (168.1 ± 7.07 mg GE/g); In addition, the NB fraction of the ethanolic extract of L. christinae Hance reveal the strongest radical-scavenging activity, antioxidant activity and protective effects against H2O2-induced injury in HUVECs.
CONCLUSIONS:
Among the four fractions of L. christinae Hance, the NB fraction showed the most potent antioxidant and endothelial protective effects, which may be attributed to its high flavonoid, phenolic contents and optimal portfolio of different active ingredients of NB fractions of the ethanolic extract of L. christinae Hance. This study might improve our understanding of the pharmacological activities of L. christinae Hance, thereby facilitating its use in disease prevention and treatment.
PMID: 29636055 PMCID: PMC5894240 DOI: 10.1186/s12906-018-2157-1 BMC Complement Altern Med. 2018 Apr 10;18(1):128. doi: 10.1186/s12906-018-2157-1. ncbi.nlm.nih.gov

Evaluation of Lysimachia christinae Hance extracts as anticholecystitis and cholagogic agents in animals.
Yang X, Wang BC, Zhang X, Liu WQ, Qian JZ, Li W, Deng J, Singh GK, Su H.
Abstract
ETHNOPHARMACOLOGICAL RELEVANCE:
Lysimachia christinae Hance is one of the herbs commonly used in traditional Chinese medicine for the treatment of cholecystitis and cholagogic efficiency.
AIMS OF THE STUDY:
The water extract of Lysimachia christinae Hance was investigated to see if it possesses cholecystitis and cholagogic effects through traditional pathways.
MATERIALS AND METHODS:
Lithocholic acid (LCA) and Escherichia coli were used to induce cholecystitis in adult guinea pigs. The present study evaluated the cholagogic effects of LCHE treatment on bile secretion and bile emptying in Sprague-Dawley rats and male Kunming mice.
RESULTS:
The results showed that LCHE not only produced excellent anticholecystitis effects but also improved lesion severity in gallbladders induced by LCA. Similarly, LCHE administered to animals in the high-dose group exhibited an antibacterial effect in acute cholecystitis, and treatment with a mid-range or a high dose of LCHE resulted in an antipyretic effect, however, three doses of LCHE treatment groups had no effect on pathological change induced by Escherichia coli in gallbladder. Treatment with a high dose of LCHE significantly promoted bile secretion (0-90min, P<0.01), and treatment with a mid-range dose also significantly promoted bile secretion (30-60min P<0.05). Furthermore, treatment with a high dose of LCHE significantly promoted bile emptying (P<0.01).
CONCLUSIONS:
Our results demonstrate that LCHE exhibits a marked anticholecystitis and cholagogic activity in animals, which supports previous claims of its use in traditional Chinese medicine.
PMID: 21524697 DOI: 10.1016/j.jep.2011.04.029 J Ethnopharmacol. 2011 Sep 1;137(1):57-63. doi: 10.1016/j.jep.2011.04.029. Epub 2011 Apr 16. ncbi.nlm.nih.gov