Psoralea corylifolia, Cullen corylifolium.  补骨脂 Bǔ gǔ zhī   Scurf pea    
Nature: Warm     FLAVOR: Pungent, acrid.
FUNCTIONS
GROUP: Replenishing Yang
1. Warm up and tone Kidney Yang.[1,2]
INDICATIONS
1. Kidney Yang deficiency: Kidney Deficiency and impotence, seminal emission and premature ejaculation, lumbago and pain in the knee joint, polyuria.[1]  Cold lumbago, frequent urination in the elderly, enuresis, diarrhea at dawn.[2]
2. External applications for corns and vitiligo- (leukoderma).
COMBINATIONS
- Spleen and Lung Qi deficiency or Kidney deficiency:Tonifies the Spleen, Lung and Kidney, aids the Kidney to grab the Qi, transforms Phlegm, redirects the Lung Qi downward, secures the Lung and the Kidney, and alleviates coughing and wheezing Astragalus & Psoralea- Xiao Er Gu Ben Ke Chuan Chong Ji.
PREPARATIONS: Decoction. Dry ripe fruit 3-9 g.[1,2]

References
Inner Path can not take any responsibility for any adverse effects from the use of plants. Always seek advice from a professional before using a plant medicinally.
Research

The cytotoxicity of psoralidin from Psoralea corylifolia.
Yang YM, Hyun JW, Sung MS, Chung HS, Kim BK, Paik WH, Kang SS, Park JG.
Abstract
A cytotoxic coumestan derivative, psoralidin (1), was isolated from the seed of Psoralea corylifolia. The IC50 values of 1 against SNU-1 and SNU-16 carcinoma cell lines were 53 and 203 micrograms/ml, respectively, indicating cytotoxic activity against stomach carcinoma cell lines.
PMID: 8792669 DOI: 10.1055/s-2006-957901 Planta Med. 1996 Aug;62(4):353-4. ncbi.nlm.nih.gov

Antibacterial compounds from the seeds of Psoralea corylifolia.
Khatune NA, Islam ME, Haque ME, Khondkar P, Rahman MM.
Abstract
Psoralidin, bakuchicin, psoralin and angelicin, isolated from the seeds of Psoralea corylifolia, showed significant antibacterial activities against a number of Gram (+) and Gram (-) bacteria.
PMID: 15030932 DOI: 10.1016/j.fitote.2003.12.018 Fitoterapia. 2004 Mar;75(2):228-30. ncbi.nlm.nih.gov

Antioxidative components of Psoralea corylifolia (Leguminosae).
Haraguchi H, Inoue J, Tamura Y, Mizutani K.
Abstract
A meroterpene and four flavonoids were isolated from the seeds of Psoralea corylifolia as antioxidative components. Their structures were elucidated by spectral data and identified as bakuchiol (1), bavachinin (2), bavachin (3), isobavachin (4) and isobavachalcone (5). In particular, meroterpene 1 and flavonoids 4 and 5 showed broad antioxidative activities in rat liver microsomes and mitochondria. They inhibited NADPH-, ascorbate-, t-BuOOH- and CCl(4)-induced lipid peroxidation in microsomes. They also prevented NADH-dependent and ascorbate-induced mitochondrial lipid peroxidation. Bakuchiol (1) was the most potent antioxidant in microsomes and the inhibition of oxygen consumption induced by lipid peroxidation was time-dependent. Furthermore, bakuchiol (1) protected human red blood cells against oxidative haemolysis. These phenolic compounds in P. corylifolia were shown to be effective in protecting biological membranes against various oxidative stresses.
PMID: 12237811 DOI: 10.1002/ptr.972 Phytother Res. 2002 Sep;16(6):539-44. ncbi.nlm.nih.gov