Oxytropis
chiliophylla. 小花棘豆Xiǎo huā jí dòu, É
dà shà,
Locoweed. Thorn
bean Family:
Leguminosae
Oxytropis falcata.
Oxytropis microphylla. Oxytropis chiliophylla, along with Oxytropis falcata, is recorded
as the official botanical origin of Tibetan medicine is regarded as the “King
of Herbs” and has been widely used in Tibetan medicines for the treatment of inflammation,
antipyretic, and bleeding for thousands of years. PART USED: Dry
whole plant FLAVOR: Slightly bitter
TOXICITY: Toxic.[1] FUNCTIONS
1. Clear Heat, counteract toxic effects, produce muscles.[1] INDICATIONS
1. High fever, laryngitis, dysentery, bleeding due to wound.[1] PREPARATIONS: Dry
whole plant 0.3-0.5 g.[1] ORIGIN: Mainly found at the altitudes of 2800–5200 meters in
Tibet and Xinjiang Urgur Autonomous Regions. DESCRIPTION: Perennial herb. Root thick and woody. Leaves stipulate;
stipules and leaf bases covered with white or yellowish woolly hairs; leaf up
to 12 cm long, petiole up to 4 cm long, glandular or eglandular, pilose, hairs
white or yellowish. Leaflets alternate, opposite, mostly whorled, subsessile,
linear-oblong to broadly oblong, 7 mm or less long, 1-2 mm broad, entire, edges
inflexed, obtuse, gland dotted and pilose. Flowers in a compact peduncled raceme,
bracteate, bracts 4-5 mm long, gland dotted and pilose; pedicel 1 mm. Calyx 10-11
mm long, teeth 3-5 mm, pilose and gland dotted. Corolla bright pink to pinkish
mauve. Vexillum 19-22 mm long. Fruit stipe 1 mm long, glabrous, fruit 21-23 mm
long, 4-5 mm broad, beaked at the tip, uniformly pilose, glands almost obscure,
almost completely bilocular, 20-30 seeded. References
[1] A Complete English Dictionary of Medicinal Terms in Chinese Acupuncture and
Herbalism 1981- Henry Lu Chinese Foundations of Natural Health- The Academy of
Oriental Heritage, Vancouver, Canada Images
1. molbiol.ru
Inner Path can not take any responsibility for any adverse effects from the
use of plants. Always seek advice from a professional before using a plant medicinally. Research
Therapeutic Effect and Mechanism of Oxytropis falcata Gel on Deep Second-Degree
Burn in Rats pdf
Oxytrodiflavanone A and Oxytrochalcoflavanones A,B: New Biflavonoids from
Oxytropis chiliophylla
Yang Liu, Norbo Kelsang, Jianghai Lu, Yingtao Zhang, Hong Liang, Pengfei Tu, Dexin
Kong,* and Qingying Zhang* Abstract
Three previously undescribed biflavonoids, oxytrodiflavanone A (1), and oxytrochalcoflavanones
A,B (2,3), were isolated from the aerial part of Oxytropis chiliophylla, together
with their putative biosynthetic monomers, i.e., (2S)-5,7-dihydroxyflavanone (4),
(2S)-7-hydroxyflavanone (5), and 2′,4′-dihydroxychalcone (6). The structures of
these compounds were elucidated by a combination analysis of spectroscopic data.
The cytotoxic activities of all the isolated compounds against PC-3 human prostate
cancer cell line are also presented.
Molecules. 2019 Apr; 24(8): 1468. Published online 2019 Apr 13. doi: 10.3390/molecules24081468
PMCID: PMC6514731PMID: 31013944 ncbi.nlm.nih.gov
Structurally Diverse Cytotoxic Dimeric Chalcones from Oxytropis chiliophylla
Yang Li, Xiaojing Zhang, Norbo Kelsang, Guangzhong Tu, Dexin Kong, Jianghai Lu,
Yingtao Zhan, Hong Lian, Orcid, Pengfei Tu, Orcid, and Qingying Zhang, Orcid Abstract
Ten isomeric cyclobutane- and cyclohexene-containing chalcone dimers, oxyfadichalcones
A–G, were isolated from the aerial parts of Oxytropis chiliophylla. These included
six new compounds and three pairs of enantiomers that are being reported from
natural sources for the first time. The relative configurations were elucidated
by spectroscopic data analysis, while the absolute configurations were determined
by comparing the experimental and calculated electronic circular dichroism spectra.
Quantitative LC-MS analysis of the main dimers from different parts of the plant
revealed their characteristic accumulation in the viscous secretion and provided
supporting evidence for the hypothesized photochemical biosynthesis. In addition,
the cytotoxic activities of all isolates against the PC-3 human prostate cancer
cell line are reported.
J. Nat. Prod. 2018, 81, 2, 307–315 https://doi.org/10.1021/acs.jnatprod.7b00736
pubs.acs.org
Rhamnocitrin glycosides from Oxytropis chiliophylla
Jun Wang, Yang Liu, Norbo Kelsang, Kewu Zeng, Hong Liang, Qingying Zhang, PengfeiTu
https://doi.org/10.1016/j.phytol.2016.11.011Get rights and content Abstract
Repeated chromatography of the n-BuOH soluble fraction from ethanol extract of
the aerial part of Oxytropis chiliophylla led to the isolation of six new rhamnocitrin
glycosides, named oxychilioflavonosides A−F (1–6), together with eight known rhamnocitrin
glycosides (7–14) of which six were isolated from the genus Oxytropis for the
first time. The structures of these compounds were elucidated by extensive spectroscopic
techniques and chemical methods. All isolated compounds were evaluated for their
anti-inflammatory activity in lipopolysaccharide (LPS)-induced BV-2 microglial
cells, and compound 11 showed potent inhibition on NO production with IC50 value
of 9.91 μM. sciencedirect.com