Psammosilene tunicoides.    Jīn tiě suǒ         
PART USED: Dried root
Nature: Warm   FLAVOR: Pungent, Bitter   TOXICITY: Slightly toxic CHANNELS: Liver
FUNCTIONS
1. Disperse coagulation, heal inflammation, expel Wind and Dampness, relieve pain.[1]
2. Dispel wind and eliminate dampness, dissipate blood stasis and alleviate pain, remove toxicity and resolve swelling.[2]
INDICATIONS
1. Fall injuries, rheumatic pain, cold stomach ache.[1]
2. External applications for carbuncle and snake bite.[1]
3. Stomachache, rheumatic arthritis, traumatic injury, traumatic hemorrhage; sores and boils, snake and insect bites for external application.[2]
CONTRAINDICATIONS: pregnancy.
PREPARATIONS: Dried root 0.3g.[1] Decoct 0.1~0.3 g, or soaked in wine. Proper dosage is for external application, pounded into powder for applying on the affected area.[2]


ORIGIN: Yunnan, Sichuan, Guizhou of China.
HABITAT: Sandy alkaline soil in pine woods, and dry waste-lands or crevices of cliffs
DESCRIPTION: Stems; prostrate, purple-green, 20-35 cm, dichotomously branched, pubescent. Leaves subsessile, 1.5-2.5 × 1-1.5 cm, adaxially pilose, base rounded, rarely broadly cuneate, apex entire, acute. Roots; brown-yellow.Inflorescence a thyrse with a terminal, lax dichasium and 2 opposite, similarly lax. Flowers in Autumn; 3-5 mm in diam. Pedicel short or flowers sessile. Petals 7-8 mm. Stamens exserted beyond calyx, 7-9 mm; anthers yellow. Capsule 7 mm. Seed brown 3 mm.
References
Inner Path can not take any responsibility for any adverse effects from the use of plants. Always seek advice from a professional before using a plant medicinally.

Research

Antifungal Cyclic Peptides from Psammosilene tunicoides

Junmian Tian, Yunheng Shen, Xianwen Yang, Shuang Liang, Lei Shan, Huiliang Li, Runhui Liu and Weidong Zhang
Abstract
Three new cyclic peptides, tunicyclins B−D, and a known cyclic peptide, psammosilenin B, were isolated from the root of Psammosilene tunicoides. The structures of new cyclic peptides were elucidated by extensive NMR and MS analysis. Tunicyclin B contains an unusual α,β-dehydrotryptophan (ΔZ-Trp) residue, previously reported from marine sponges and bacteria. Tunicyclin D showed a broad spectrum of antifungal activity against Candida albicans (SC5314), Candida albicans (Y0109), Candida tropicalis, Candida parapsilosis, and Cryptococcus neoformans (BLS108) with MIC80 values of 4.0, 16.0, 0.25, 1.0, and 1.0 μg mL−1, respectively.
J. Nat. Prod. 2010, 73, 12, 1987–1992 Publication Date:November 11, 2010 https://doi.org/10.1021/np100363a pubs.acs.org