Malus asiatica.  Huā hóng  Crabapple   Family: Roseaceae      
Nature- neutral    FLAVOR:  Sour-sweet     CHANNEL:  Heart, Liver, Lung
FUNCTIONS
1. Quench thirst.[1,2] Transform Qi stagnation, constrict seminal ejaculation.[1] Obstructive.[2]
INDICATIONS
1. Diabetes, diarrhea, seminal emission.[1,2]
CONTRAINDICATIONS: Excessive consumption could cause sleepiness and weakened Jing luo.[1] Crabapples are obstructive and therefore not recommended for people with constipation.[2]
COMBINATIONS
PREPARATIONS: Boil or raw or fresh juice.[1]


References
Inner Path can not take any responsibility for any adverse effects from the use of plants. Always seek advice from a professional before using a plant medicinally.

Research

Wu Shan Shen Cha (Malus asiatica Nakai. Leaves)-Derived Flavonoids Alleviate Alcohol-Induced Gastric Injury in Mice via an Anti-Oxidative Mechanism
Bihui Liu, Chengfeng Zhang, Jing Zhang, andXin Zhao*
Abstract
Wu Shan Shen Cha is the leaf of Malus asiatica Nakai., a special type of tea that is consumed in the same way as green tea. To study the effect of Wu Shan Shen Cha-derived flavonoids (WSSCF) on lesions in the stomach, a 15% hydrochloric acid–95% ethanol (volume ratio 4:6) solution was used to induce gastric injury in mice. The degree of gastric injury was assessed using tissue specimens, and the effects of WSSCF on the serum levels of antioxidant enzymes were investigated. The results showed that WSSCF could alleviate the damage of the gastric mucosa and gastric wall caused by the hydrochloric acid–ethanol solution, decrease the tissue and serum levels of malondialdehyde (MDA) in mice with gastric injury, and increase the serum levels of superoxide dismutase (SOD) and glutathione (GSH). The results of quantitative polymerase chain reaction (qPCR) showed that WSSCF could increase the mRNA expression of Mn-SOD, Cu/Zn-SOD, catalase (CAT), endothelial nitric oxide synthase (eNOS), and neuronal nitric oxide synthase (nNOS) in tissue specimens from mice with gastric injury and decrease the expression of cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS). At the same time, the results of the high concentration of WSSCF (WSSCFH) group were closer to those of the drug (ranitidine) treatment group. Wu Shan Shen Cha-derived flavonoids had a good antioxidant effect, so as to play a preventive role in alcoholic gastric injury.
Biomolecules 2019, 9(5), 169; https://doi.org/10.3390/biom9050169
Published: 3 May 2019
Special Issue Oxidative Damage on Biomolecules and Antioxidants mdpi.com