Guaiacum officinale. G. sanctum   Guaiacum, Tree of life, Guaiac   Family: Zygophyllaceae  
Pronounced gwai· uh· km. Guaiacum officinale is the national flower of Jamaica.
PART USED: Heart-wood resin.
TASTE: Irritating ODOR: Aromatic
ACTIONS
GROUP: The Musculo-Skeletal System- Antirheumatics
1. Antirheumatic.[3]
2. Alterative.
3. Anti-inflammatory.[3]
4. Diuretic.[3]
5. Diaphoretic.[3]
6. Laxative - mild.[1,2,3]
INDICATIONS
1. Chronic rheumatism. Rheumatoid arthritis.[1,2,3] Subacute and chronic rheumatism. Gout,[3]- as a prophylactic.
2. Tonsillitis.
3. Skin disorders generally.
4. Syphilis.
5. "Impure blood".
COMBINATIONS
PREPARATIONS
Dried wood  1-2 g, or as decoction 1:20.
Wood fluid extract 1: 1 in 80% alcohol  1-2 ml.  2-4 ml.[3]
Wood tincture  1:5 in 90% alcohol  1-4 ml.[1,2,3]
Guaiacum tincture (BPC1949) 2-4 ml.[3]
               
ORIGIN: Indigenous to the West Indies, South America and Florida.
DESCRIPTION: Evergreen tree. The wood is normally sold as shavings. The heart-wood is greenish brown, heavier than water. The resin, which accounts for about 20%, is produced by firing the logs, and colled when melted.
References
Inner Path can not take any responsibility for any adverse effects from the use of plants. Always seek advice from a professional before using a plant medicinally.
Constituents
References

Anti-rheumatoid and anti-oxidant activity of homeopathic Guaiacum officinale in an animal model.
Sarkar A, Datta P, Das AK, Gomes A.
Abstract
BACKGROUND:
Homeopathy is a popular form of complementary and alternative medicine. Guaiacum extract is said to be useful for pain and inflammation, but there appears to be no scientific evidence to support this.
AIMS:
The aim of the present study was to evaluate the anti-rheumatic and anti-oxidant activity of homeopathic preparations of Guaiacum officinale (Gua) on experimental animal model.
DESIGN:
Rheumatoid arthritis (RA) was induced in male albino rats by Freund's complete adjuvant (FCA) at a dose of (0.25 mg heat killed Mycobacterium tuberculosis/ml of emulsion). Gua mother tincture (MT) (prepared from the latex part of the plant) (MT), Gua 30cc and 200cc were purchased commercially from King Company, Kolkata, India. Male albino Wistar rats (130 ± 10 g) were divided into 6 groups: Sham control; Arthritis control; Standard treatment indomethacin (0.25 mg 100 g(-1) p.o. × 5 alternative days), Gua MT (1 ml kg(-1) p.o. × 5 days) treated; Gua (30c 1 ml kg(-1) p.o. × 5 days) treated; Gua (200c; 1 ml kg(-1) p.o. × 5 days) treated. Anti-rheumatic activity was examined through physical, urinary, serum parameters. All the results were expressed in terms of mean ± SEM (statistical error of mean n = 6) at each dose level. The level of significance was determined through one-way analysis of variance (ANOVA), p < 0.05 was considered significant.
RESULTS:
It was observed that body weight, ankle and knee diameter, urinary parameters (hydroxyproline (OH-P), glucosamine, calcium (Ca(2)(+)), creatinine (CRE), phosphate (PO4(3)(-))), serum ACP (acid phosphatase)/ALP (alkaline phosphatase)/Ca(2+)/CRE/PO4(3-)/gamma-glutamyl transferase (GGT)/Lipid peroxidation (LPO)/Glutathione (GSH)/Superoxide dismutase (SOD)/Catalase, serum GGT, serum interleukins like IL-1ß/CINC-1/PGE2/TNF-a/IL-6, IL-12/IL-4/IL-6 levels were significantly affected. After treatment with Guaiacum in all 3 regimes was associated with normalization of these parameters compared to control group.
CONCLUSION:
These findings suggest that homeopathic G. officinale possesses anti-rheumatic and anti-oxidant activity in experimental animal and these activities may be more significant in higher potencies.
PMID: 24685418 DOI: 10.1016/j.homp.2013.08.006  Homeopathy. 2014 Apr;103(2):133-8. doi: 10.1016/j.homp.2013.08.006. ncbi.nlm.nih.gov